What Are GLP-1 Agonists and How Do They Work?

15 November, 2024  |  Holy Winter - Healthcare Writer

What Are GLP-1 Agonists and How Do They Work?

GLP-1 agonists, such as Wegovy and Mounjaro, mimic a naturally occurring hormone in your body that helps regulate blood sugar levels, appetite, and digestion. These medications slow down how quickly food leaves your stomach, making you feel fuller for longer, reducing hunger and promoting gradual, sustainable weight loss.

Common Side Effects

It’s normal to experience some side effects when starting treatment as your body adjusts. The most common ones include:

• Nausea
• Vomiting
• Diarrhea or constipation
• Bloating or abdominal discomfort

These symptoms often improve over time. Eating smaller, more frequent meals and avoiding high-fat or greasy foods can help.

Rare but Serious Side Effects

Although uncommon, GLP-1 agonists can cause serious side effects such as:

1. Pancreatitis (inflammation of the pancreas)
   Symptoms: Severe abdominal pain that may radiate to your back, nausea, vomiting, and fever.
2. Gallbladder problems
   Symptoms: Persistent pain in the upper right abdomen, nausea, vomiting, fever, or yellowing of the skin (jaundice).
3. Thyroid issues (rare)
   Symptoms: Swelling or a lump in the neck, trouble swallowing, or persistent hoarseness.

If you experience any of these symptoms, stop taking the medication immediately and seek urgent medical care.

Monitoring for Side Effects

Your safety is our top priority. If you experience any side effects, even if you think they’re minor, please let us know right away. This helps us monitor your treatment and make adjustments if necessary.

When to Seek Medical Help

Contact a healthcare professional right away if you experience:

• Severe or persistent nausea, vomiting, or diarrhea.
• Symptoms of dehydration (e.g., extreme thirst, dark urine, dizziness).
• Symptoms listed above for serious side effects.

Importance of an Active Lifestyle

Incorporating regular exercise is vital for optimising your results. Physical activity improves metabolism, maintains muscle mass, and enhances overall well-being. Even light activities such as walking or yoga can make a big difference. Aim for at least 150 minutes of moderate exercise per week or as much as your physical ability allows.

Diet Tips for Success

• Balanced Diet: Include a variety of vegetables, lean proteins, whole grains, and healthy fats.
• Protein Intake: Sufficient protein is crucial for satiety and preserving muscle mass. Include protein sources like eggs, chicken, tofu, or legumes in your meals.
• Avoid Rapid Weight Loss: Losing weight too quickly can result in muscle loss, leaving you feeling weak and fatigued. Aim for 1 - 2 pounds of weight loss per week.
• Hydration: Drink plenty of water throughout the day to stay hydrated and support digestion. Aim for at least 6–8 glasses daily unless otherwise advised. Please note that this is general guidance. Everybody will have their own individual requirements when it comes to hydration.

Additional Lifestyle Tips

• Limit alcohol and sugary beverages as they can interfere with your progress.
• Plan meals and snacks to avoid overeating or skipping meals.
• Listen to your body - rest when needed and adjust portion sizes as your appetite changes.

In Summary

• GLP-1 agonists are powerful tools for weight management but require commitment to healthy lifestyle changes.
• Be mindful of common and rare side effects and report any concerns to us immediately.
• Focus on a balanced diet, adequate hydration, and regular exercise for the best results.

We’re here to support you every step of the way. Please don’t hesitate to reach out with questions or concerns.

Good luck on your weight loss journey.

Kind Regards,
The Clinical Team at IQ Doctor